Delta Dental of Michigan, Delta Dental of North Carolina and OraLiva Inc. Announce Multi-State Launch of AI-Powered Oral Cancer Test
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Delta Dental of Michigan, Delta Dental of North Carolina and OraLiva Inc. Announce Multi-State Launch of AI-Powered Oral Cancer Test
Read More
If your dentist has recommended an OraLiva test, or you simply want to know more, this page helps you understand what the test is, what to expect, and what your results may mean.
OraLiva gives your dentist a precise, painless way to evaluate oral spots during a regular visit using a simple brush sample and AI-assisted analysis.
A soft brush collects cells from any spot in your mouth that looks unusual, such as a white patch, a red area, or a sore that has not healed. The sample is then analyzed by OraLiva’s AI-powered platform trained on millions of cell images.
“Think of it like a routine screening for your mouth. Quick, simple, and designed to find problems before they become serious.
Oral cancer affects over 54,000 Americans each year but when caught early, survival rates are dramatically higher.
Most oral spots are completely harmless. The OraLiva test helps your dentist know for certain, so you're not left wondering.
No scalpel. No stitches. No specialist referral just to get an answer.
During your routine exam, your dentist notices an area in your mouth worth checking a white patch, red area, or sore that hasn’t cleared up. It doesn’t necessarily mean anything is wrong; your dentist simply wants to be thorough.
Using a soft, specially designed brush, your dentist gently rotates it over the area to collect surface cells. Most patients say it feels like a slightly firmer toothbrush. There’s no cutting, no injection, and no anesthesia needed.
Your sample is packaged and sent directly to OraLiva’s laboratory, where it is processed and analyzed by our AI-powered ONC In-Cyt platform.
A detailed digital report including a numerical risk score is sent to your dentist, typically within a few days. Your dentist will then walk you through what the results mean and recommend any next steps.
Your dentist will receive a detailed report including a numerical risk score, along with a plain-language summary. Here’s what the possible outcomes generally mean.
Reassuring
No abnormal cells were detected. Your dentist may simply continue to monitor the area at future visits.
Follow Up
Some unusual cells were found, but they are not clearly precancerous. This does not mean you have cancer.
Specialist Review
Abnormal cells with precancer potential were identified. Early detection means your care team can act before it progresses.
Whatever your result, your dentist is your partner in next steps. OraLiva’s report is designed to empower your care team to guide you confidently not to alarm you.
The OraLiva brush biopsy test is billed directly through your dental practice as a diagnostic procedure. In most cases, your dental office will submit the claim to your insurance provider on your behalf.
Coverage varies by plan. OraLiva works with a growing network of providers, including Delta Dental of Michigan and Delta Dental of North Carolina. We recommend checking with your dental office before your appointment to confirm your specific coverage.
If you are uninsured or your plan does not cover the test, our billing team can discuss self-pay options and provide a cost estimate ahead of your appointment. Please contact us directly so we can help find the best path forward for you.
OraLiva testing is typically eligible for payment through Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA). We recommend confirming eligibility with your plan administrator.
Most patients say it feels like a slightly firmer toothbrush being gently pressed against the inside of their mouth. It's brief and well-tolerated. If you're concerned about sensitivity, let your dentist know a topical anesthetic can be used if needed.
Most oral cancer is discovered late resulting in just a 60% survival rate at 5 years. When caught, late stage treatment is disfiguring and incredibly expensive. Even with routine visual exams, subtle dysplastic lesions are often mistaken for benign conditions or ignored until they become malignant.
OraLiva is a reimbursable, accurate and actionable test to support clinical decisions. Our simple brush test takes less than a minute to collect and helps the provider remove the uncertainty about whether to refer a patient or not to a specialist.
No. Most oral cancers are diagnosed too late despite visual exams. Even oral pathologists disagree about 70%, of the time on what they diagnose as mild oral dysplasia. OraLiva' test helps dental providers triage lesions to catch oral disease earlier, improving patient outcomes and reducing unnecessary biopsies.
Yes! Many dental plans cover the collection under CDT D7288 although D7287 may be used for some plans. Coverage varies by plan so please confirm with the patient dental plan.
After receiving the sample OraLiva will bill the patient’s medical insurance for the analysis.
OraLiva’s test is built on cytology enhanced by advanced imaging and AI-driven diagnostic models. Using a soft-bristle brush, the test collects a transepithelial cell sample that includes surface and basal layers where dysplasia typically arises. The sample is processed in a CLIA-certified laboratory and analyzed with proprietary algorithms that evaluate nuclear morphology, biomarker expression, and cellular phenotype frequencies. Results are compared against the largest oral cytomics databases ever assembled, which allows OraLiva to generate a reproducible risk index for each lesion.
Yes. OraLiva’s technology and diagnostic models have been documented in multiple peer-reviewed publications in oncology and dental research journals. These studies have undergone independent review and replication, ensuring that the science is transparent and credible. A full list of publications is available on OraLiva’s website.
Whether your dentist has already recommended OraLiva or you’d like to bring it up at your next visit, protecting your oral health starts here.send this note to your doctor to ask if they have our test
Ask your dentist if an OraLiva test is right for you at your next appointment.
Our billing team is ready to help with insurance questions, coverage estimates, and payment options.
